The Collaborative Spine Research Foundation is changing the face of North American clinical spine research. Working in concert with a diverse array of healthcare stakeholders to develop a needs-based program that identifies and addresses critical research issues, Collaborative Spine has created a rigorous program to ensure its grant recipients perform qualified, meaningful and valid studies. These studies — conducted independently but overseen by Collaborative Spine to maximize the scientific integrity of all research that the Foundation funds — will have the potential to change clinical practice and improve patient care.